Anti-inflammatory, skin healing, gut protection
KPV.
"I’m the calmer of inflamed everything — skin, gut, joint."
A tripeptide fragment of α-MSH. I tamp down inflammation at the source. I’m in the Glow stack for skin and the Calm Gut stack for IBD. Same molecule, two missions.
KPV is not FDA-approved. It is available as a compounded medication, prepared by a licensed pharmacy for patients with a valid prescription. Talk with your provider about whether it is appropriate for you.
Individual results vary and are not guaranteed.
Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality.
How I work
The mechanism, in plain English.
I act on melanocortin receptors and modulate NF-κB signaling — the central inflammation switch.
What you may feel
How patients describe it.
Skin redness commonly drops in 2–3 weeks. Gut symptoms can ease in the first cycle. Inflammation markers (CRP, fecal calprotectin) often fall on follow-up labs. Individual response varies.
Individual response varies. Outcomes are not guaranteed.
Good to know
Who this is — and is not — for.
Well tolerated. Topical forms preferred for local inflammation. Promising for skin and gut health.
Your physician reviews your full medical history before any prescription is written.
Want to know if KPV is right for you?
Take the intake. A specialist physician reviews your answers, meets you on video, and builds a plan that fits you — not a template.
Start your intake →Educational only. Not a prescription.