Metabolic regulation, mitochondrial health, exercise mimetic
MOTS-c.
"I rewrite how your cells make energy. From inside the mitochondria."
A mitochondrial-derived peptide that supports insulin sensitivity, VO2 max, and metabolic resilience.
MOTS-c is not FDA-approved. It is available as a compounded medication, prepared by a licensed pharmacy for patients with a valid prescription. Talk with your provider about whether it is appropriate for you.
Individual results vary and are not guaranteed.
Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality.
How I work
The mechanism, in plain English.
I’m encoded in mitochondrial DNA itself. I regulate metabolic homeostasis, AMPK signaling, and fat oxidation. Not a steroid, not a stim — a metabolic regulator.
What you may feel
How patients describe it.
VO2 max often climbs in 4–8 weeks of consistent use. Insulin sensitivity tends to improve on follow-up labs. Response is training- and dose-dependent.
Individual response varies. Outcomes are not guaranteed.
Good to know
Who this is — and is not — for.
Limited human data. Anecdotal reports suggest improved energy and body composition. Promising but still experimental.
Your physician reviews your full medical history before any prescription is written.
Want to know if MOTS-c is right for you?
Take the intake. A specialist physician reviews your answers, meets you on video, and builds a plan that fits you — not a template.
Start your intake →Educational only. Not a prescription.